Langer Lab (2023)

I worked at the OHSU Knight Cancer Institute as a participant in the Cell, Developmental & Cancer Biology Summer Research Internship Program. In the Langer lab at the Cancer Early Detection Advanced Research Center (CEDAR), I studied fibroblast plasticity in pancreatic cancer. More specifically, I investigated crosstalk mechanisms between cancer cells and stromal cells, as well as environmental cues that trigger cancer cell differentiation. To this end, I studied the influence of exogenous metabolites on TGFβ1-driven activation of human Pancreatic Stellate Cells towards a myofibroblast-like cancer-associated fibroblast (myCAF) state.